Testicular steroidogenesis after human chorionic gonadotropin desensitization in rats.
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چکیده
منابع مشابه
Testicular steroidogenesis after human chorionic gonadotropin desensitization in rats.
When a single injection of 500 I.U. of human chorionic gonadotropin (hCG) is given to rats there is an initial acute rise of plasma testosterone and of testicular content for both cyclic AMP and testosterone. This response correlates with an increase in both lyase and 17 alpha-hydroxylase activities. Thereafter both plasma and testicular testosterone decline and do not increase after a second i...
متن کاملHyperglycosylated human chorionic gonadotropin in serum of testicular cancer patients.
BACKGROUND Hyperglycosylated human chorionic gonadotropin (hCG-h) contains larger and more complex carbohydrate chains than regular human chorionic gonadotropin (hCG). hCG-h is thought to be the major form of hCG produced by testicular cancers and it has been suggested to play a key role in tumor invasion, but studies on hCG-h in testicular cancer are limited. We studied whether serum hCG is hy...
متن کاملEffects of human chorionic gonadotropin on the normal testicular tissue of rats.
PURPOSE To investigate the effects of human chorionic gonadotropin (hCG) on the testicular tissue of young male rats. METHODS Male Wistar rats were assigned to groups (10 rats/group).Control Group received subcutaneous saline solution; Group 1 received hCG 50 UI/Kg/dose; and Group 2 received hCG 100 UI/Kg/dose, daily for 15 days. Half was submitted to bilateral orchiectomy on the 16th day and...
متن کاملHuman Chorionic Gonadotropin
A highly active preparation of human chorionic gonadotropin has been obtained by simple methods of column chromatography on diethylaminoethyl Sephadex and Sephadex G-100. The preparation appeared homogeneous by disc and immunoelectrophoresis, ultracentrifugation, and end group analysis. It assayed at 12,000 i.u. per mg by the rat prostrate gland and accessory sex organ method. The ~20,~ value w...
متن کاملHuman chorionic gonadotropin (hCG) versus magnesium sulfate to arrest preterm
Introduction: Considering the high incidence of preterm labor and its known complications, and that human myometrium contains receptors for human chronic gonadotropin (hCG) and that hCG can inhibit myometrial contractions on vitro, made me study treating effects of hCG on preterm labor. This clinical trial study was carried out to compare the effect of hCG, and magnesium sulfate (mgso4) on pre...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1979
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)50457-9